InhaltsangabeAngiopoietins.- HIF-1? and Cancer Therapy.- Chemokines.- Angiogenesis Inhibition in Cancer Therapy.- Vascular Integrins: Therapeutic and Imaging Targets of Tumor Angiogenesis.- PDGF and Vessel Maturation.- Lymphangiogenesis in Cancer: Current Perspectives.- Compounds in Clinical Phase III and Beyond.- Metronomic Chemotherapy: Principles and Lessons Learned from Applications in the Treatment of Metastatic Prostate Cancer.- Targeting Inflammatory Cells to Improve Anti-VEGF Therapies in Oncology.- Antibody-Based Vascular Tumor Targeting.- Caveolae and Cancer.

Introduction. Angiopoietins.- HIF-1a and cancer therapy.- Chemokines.- Platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF) and their receptors: biological functions and role in malignancy.- Vascular integrins: therapeutic and imaging targets of tumor angiogenesis. PDGF and vessel maturation.- Lymphangiogenesis in cancer: current perspectives.- Therapeutic compounds in clinical studies of Phase III trials and beyond.- Metronomic chemotherapy - principles and lessons learned from applications in the treatment of metastatic prostate cancer.- Targeting inflammatory cells to improve anti-VEGF therapies in oncology.- Antibody-based vascular tumor targeting. Caveolae and cancer.