The aim of this guide is to provide clinicians with practical reference for the management of hypertensive patients with other cardiovascular risk factors, which originate from impaired metabolic functions. With the aid of carefully selected, paradigmatic case studies, the physician will find sound advice for the best approach to common but often under-recognized clinical situations, and answers to practical questions that arise when a specific condition is not directly addressed in the guidelines. Question-and-answer sections will help the reader to identify at a glance the most complex steps in the diagnostic and therapeutic process.

In a real world clinical setting, the hypertensive patient rarely presents with hypertension as the only cardiovascular risk factor, and is more likely to be affected by other metabolic risk factors, such as impairment of lipid metabolism, glucose homeostasis, and purine metabolism, and by overweight or obesity. These cases will serve as abasis for analyzing best practice, highlighting problems in diagnosis and treatment, and selecting the most appropriate management of patients with metabolic risk factors in everyday practice.

Arrigo F.G. Cicero, is Board graduated in Clinical Pharmacology, Full-time clinical researcher by the Medicine and Surgery Department of the University of Bologna (Italy). He also works as medical consultant by the S. Orsola-Malpighi University Hospital of Bologna (Italy), managing an outpatient clinic for patients affected by hyperlipidemia and/or hypertension. He is author of more than 360 full papers published in international scientific journals. He is also member of the editorial board of some international peer-reviewed journals, among which High Blood Pressure& Cardiovascular Prevention, Archives of Medical Science - Atherosclerotic Diseases journal, and Clinical Lipidology. He acts as reviewer for main international journals in the field of internal medicine and cardiovascular disease prevention, among which BMJ, the Lancet, PLOS one, Annals of Medicine, Circulation, Hypertension, Atherosclerosis, and American Journal of Cardiology.<

Clinical case 1: Adult Patient with Hypertension and Metabolic Syndrome.- Clinical case 2: Adult Patient with Hypertension and Diabetes.- Clinical case 3: Adult Patient with Hypertension and Familial Hypercholesterolemia.- Clinical case 4: Adult Patient with Hypertension and Hypertriglyceridemia.- Clinical case 5: Adult Patient with Hypertension and Obesity.- Clinical case 6: Adult Patient with Hypertension and Gout.